Single Cell Surgery with Monodispersed Microbubbles Generated by a Pulsed Discharge of Microelectric Knife

نویسندگان

  • Hiroki Kuriki
  • Yoko Yamanishi
  • Shinya Sakuma
  • Satoshi Akagi
  • Fumihito Arai
چکیده

We have successfully operated enucleation of oocyte by using microelectric knife without any thermal collateral damage. Minimally-invasive cellular-scale ablation was achieved by the mono-dispersed microbubbles which were generated by a pulse discharge of microelectrode. The discharged output power and conductive area of microelectrode were controlled by glass shell insulation around the copper microwire. A small space which is called “bubble reservoir” between the wire and glass tip contributes to stabilize the electric discharge and directional bubble generation.

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تاریخ انتشار 2012